Bounds for parametric sequence comparison
نویسندگان
چکیده
منابع مشابه
Bounds for Parametric Sequence Comparison
We consider the problem of computing a global alignment between two or more sequences subject to varying mismatch and indel penalties. We prove a tight 3(n=2 )+O(n log n) bound on the worst-case number of distinct optimum alignments for two sequences of length n as the parameters are varied. This re7nes a O(n) upper bound by Gus7eld et al., answering a question posed by Pevzner and Waterman. Ou...
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For as long as biologists have been computing alignments of sequences, the question of what values to use for scoring substitutions and gaps has persisted. In practice, substitution scores are usually chosen by convention, and gap penalties are often found by trial and error. In contrast, a rigorous way to determine parameter values that are appropriate for aligning biological sequences is by s...
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Let = be a non-negative matrix. Denote by the supremum of those , satisfying the following inequality: where , , and also is increasing, non-negative sequence of real numbers. If we used instead of The purpose of this paper is to establish a Hardy type formula for , where is Hausdorff matrix and A similar result is also established for where In particular, we apply o...
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ژورنال
عنوان ژورنال: Discrete Applied Mathematics
سال: 2002
ISSN: 0166-218X
DOI: 10.1016/s0166-218x(01)00206-2